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产品目录

Cleaved-COL4A3 (L1425)抗体图片
产品货号:
Z30147
中文名称:
Cleaved-COL4A3 (L1425)抗体
英文名称:
Anti-Cleaved-COL4A3 (L1425) Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-Cleaved-COL4A3 (L1425) Antibody
指标别名COL4A3;Tumstatin;Goodpasture antigen;Collagen alpha-3(IV) chain
克隆性Polyclonal
检验物种human
应用范围WB,ELISA
基因名称COL4A3
抗体来源Rabbit
抗体类型IgG
免疫原Synthesized peptide derived from human COL4A3
计算分子量162KD
成分Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
纯化方式The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度1mg/mL
产品形态溶液
保存条件-20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。
背景资料Collagen alpha-3(IV) chain is a protein that in humans is encoded by the COL4A3 gene.Type IV collagen,the major structural component of basement membranes,is a multimeric protein composed of 3 alpha subunits.These subunits are encoded by 6 different genes,alpha 1 through alpha 6,each of which can form a triple helix structure with 2 other subunits to form type IV collagen.This gene encodes alpha 3.In the Goodpasture syndrome,autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli.The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-terminal domain of the protein.A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis.This gene is also linked to an autosomal recessive form of Alport syndrome.The mutations contributing to this syndrome are also located within the exons that encode this C-terminal region.Like the other members of the type IV collagen gene family,this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter.
Uniprot IDQ01955
基因名全称Collagen alpha-3(IV) chain
蛋白名全称Collagen alpha-3(IV) chain
推荐稀释比WB 1:500~1:2000
ELISA 1:5000

相关搜索:Cleaved-COL4A3 (L1425)抗体Cleaved-COL4A3 (L1425)多抗Anti-Cleaved-COL4A3 (L1425) Antibody
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